The Health Implication of Enterohaemorrhagic Escherichia coli (EHEC) 0157:H7: A Review on Haemolytic Uraemic Syndrome

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Haemolytic uraemic syndrome associated with a family cluster of enterohaemorrhagic Escherichia coli.

In early 1995 an outbreak of 23 cases of haemolytic uraemic syndrome (HUS) occurred in children (ranging from four months to 12 years of age) in South Australia.1 Twenty of the cases were managed in a tertiary paediatric hospital in Adelaide, where 18 (90%) required dialysis.2 A 4-year-old died and 12 months after discharge 5 of the surviving children still had significantly impaired renal func...

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An outbreak of haemolytic uraemic syndrome (HUS) among children caused by infection with sorbitol-fermenting enterohaemorrhagic Escherichia coli O157:H- (SF EHEC O157:H-) occurred in Germany in 2002. This pathogen has caused several outbreaks so far, yet its reservoir and routes of transmission remain unknown. SF EHEC O157:H- is easily missed as most laboratory protocols target the more common ...

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Validation of treatment strategies for enterohaemorrhagic Escherichia coli O104:H4 induced haemolytic uraemic syndrome: case-control study

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The haemolytic uraemic syndrome (HUS) is characterized by the triad of thrombocytopenia, microangiopathic haemolytic anaemia and acute renal failure. HUS may be classified as either diarrhoeal-associated or non-diarrhoeal/atypical (aHUS). aHUS has recently been shown to be a disease of complement dysregulation, with 50% of cases involving the complement regulatory genes, factor H (CFH), membran...

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ژورنال

عنوان ژورنال: Asian Journal of Research in Medical and Pharmaceutical Sciences

سال: 2019

ISSN: 2457-0745

DOI: 10.9734/ajrimps/2019/v7i430129